Pablo NAVARRO Lab

Immunofluorescence of Nanog (red) and H3K36me3 (green) of a single DAPI-stained ES cell.
Immunofluorescence of Nanog (red) and H3K36me3 (green) of a single DAPI-stained ES cell.

WE combine biochemistry, molecular biology and state-of-the-art imaging approaches in mouse ES cells to investigate the role of regulatory networks in cellular decision-making processes.

  1. The properties emerging from and the constrains imposed by the modular and dynamic organisation of the network.
  2. The epigenetic mechanisms ensuring the rapid reestablishment of the network after mitosis and, conversely, those promoting its dismantling upon differentiation. 
  3. The involvement of non-coding RNAs in ES cells epigenetics.

H3K4me3 (blue) and H3K27me3 (red) profiles across a 300kb-long genomic region
Paris, FRANCE
Paris, FRANCE

INSTITUT PASTEUR

Department of Developmental and Stem Cell Biology

ANR REVIVE LabEx

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Created by Pablo Navarro